AKOS B014321 - Names and Identifiers
AKOS B014321 - Physico-chemical Properties
Molecular Formula | C16H12ClNO
|
Molar Mass | 269.73 |
Density | 1.21±0.1 g/cm3(Predicted) |
Melting Point | 115.0 to 119.0 °C |
Boling Point | 465.5±30.0 °C(Predicted) |
Solubility | DMSO: ≥20mg/mL |
Appearance | powder |
Color | off-white to light tan |
Storage Condition | Inert atmosphere,2-8°C |
Sensitive | Light Sensitive |
AKOS B014321 - Risk and Safety
Hazard Symbols | Xi - Irritant
|
WGK Germany | 3 |
Hazard Class | IRRITANT |
AKOS B014321 - Preparation solution concentration reference
| 1mg | 5mg | 10mg |
---|
1 mM | 3.707 ml | 18.537 ml | 37.074 ml |
5 mM | 0.741 ml | 3.707 ml | 7.415 ml |
10 mM | 0.371 ml | 1.854 ml | 3.707 ml |
5 mM | 0.074 ml | 0.371 ml | 0.741 ml |
Last Update:2024-01-02 23:10:35
AKOS B014321 - Reference Information
biological activity | Oncrasin-1 (Onc-1) is an effective inhibitor of RNA polymerase II with anti-tumor activity, which can kill a variety of human lung cancer cells with K-Ras mutations. Oncrasin-1 drive abnormal aggregation of protein kinase C iota (PKCι) in sensitive nuclei (non-drug resistant cells). |
target | TargetValue K-ras () RNA polymerase II () PKCι () |
Target | Value |
Last Update:2024-04-09 21:54:55